Summary: Bovine coccidiosis is one of the most common diseases in livestock, which leads to large economic losses in addition to high mortality for animals, and despite the large number of studies on this disease, studies on the biochemical and physiological effects of this parasite are still limited, especially the effect of parasite infection on some variables Blood in cows, and from this standpoint the current study was conducted, which included measuring the levels of malondaldehyde ) MDA) , and glutathione(GSH) .As the study included a number of adult cows (40) and a number of young calves 2-3 months old (35 calves). A stool sample (5 grams) and a blood sample (10 cm) were taken from each animal. The affected animals were diagnosed through the detection of the visible symptoms on animal and stool examination The stool was laboratory treated through an examination, using floatation and direct smaer methods to find ovarian cysts of the parasite, and the percentage of infection was determined using the modified Macmaster method, and then biochemical tests were performed on blood samples of both infected and healthy cows. The color test method was used to measure the level of malondialdehyde and the modified Almanns method to measure the level of glutathione in plasma. The results of the current study showed that infection with the parasite increased lipid peroxidation in the blood plasma of both calves and cows, respectively (4.3423 ± 1.0238, 7.4918 ± 1.4232) compared with normal cows and calves (2.3423 ± 0.465, 2.9537 ± 1.063), while it led to a decrease in glutathione level in Both of the infected cows (7.3041 ± 2.8213) compared with healthy cows (11.2322 ± 2.2628), and there was no significant difference in the level of glutathione between infected and uninfected calves.
